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=== Tissue-of-origin mapping by normal, cancer and inflammation reference === * Dr. Zhang said maybe we can integrate cancer,normal and inflammation samples as the reference so that we can mapping the plasma to differnet tissue, different stage, just like the 'GPS' * Take the normal samples as the background and don't forget to do the cross-validation and then estimate each plasma to differenet refernece and then give the pvalue * Very important and interesting idea come out from Dr. Zhang again. Dr. Zhang said we can merge one disease reference and one normal reference and for that diease, we would get more strong signals,compared with single reference (10/16/2016). * differrent stastic Z-score, Baysian score. * kedney cancer as the reference since we have samples.
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