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===Data Description=== *RRBS Protocol: [[File:Myers Lab RRBS Protocol 6-18-2010.pdf]] *RRBS Analysis Protocol: [[File:RRBS Guide-Baraham.pdf]] *Normal tissues from RRBS data were downloaded from the ENCODE USCS genome browser [1]. Raw sequence data from 16 tissues were collected (Supplementary Table). Sequences were mapped to the bisulfite-converted human genome (NCBI hg19) using Bismark [2], after trimming the first three nucleotides, using the following parameters: --bowtie2 --phred64-quals --fastq -L 20 -N 1. *1.RRBS and ENCODE, http://hgdownload.cse.ucsc.edu/goldenPath/hg19/encodeDCC/wgEncodeHaibMethylRrbs/. *2.Krueger, F. and S.R. Andrews, Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications. Bioinformatics, 2011. 27(11): p. 1571-2. * Main important tissues were selected and merge to prediction model {| {{table}} | align="center" style="background:#f0f0f0;"|'''ENCFF000LWX''' | align="center" style="background:#f0f0f0;"|'''RRBS''' | align="center" style="background:#f0f0f0;"|'''uterus''' | align="center" style="background:#f0f0f0;"|'''adult''' | align="center" style="background:#f0f0f0;"|'''female''' | align="center" style="background:#f0f0f0;"|'''44 year''' | align="center" style="background:#f0f0f0;"|'''36bp''' | align="center" style="background:#f0f0f0;"|'''Illumina Genome Analyzer IIx''' |- | ENCFF000LXB||RRBS||uterus||adult||female||44 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVO||RRBS||lung||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVR||RRBS||lung||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVA||RRBS||kidney||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVB||RRBS||kidney||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LUT||RRBS||breast||adult||female||21 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LUV||RRBS||breast||adult||female||21 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LUQ||RRBS||brain||adult||male||66 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LUU||RRBS||brain||adult||male||66 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LWS||RRBS||stomach||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LWW||RRBS||stomach||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVU||RRBS||pancreas||adult||male||71 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVW||RRBS||pancreas||adult||male||71 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LWO||RRBS||zone of skin||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LWP||RRBS||zone of skin||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVI||RRBS||mononuclear cell||adult||unknown||54 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVK||RRBS||mononuclear cell||adult||unknown||54 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVJ||RRBS||liver||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | ENCFF000LVN||RRBS||liver||adult||female||83 year||36bp||Illumina Genome Analyzer IIx |- | |}
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