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===Human DMR 220k probe set (May 2010)=== *This probe set was designed based on the following targets: **core: ***~20,000 DMRs provided by Andy Feinberg's group at JHU. These DMRs were identified by the CHARM analysis; ***~30,000 targets provided John Stamatoyannopoulous's group at UW. These targets were mainly selected based on DNase I sensitive regions. **imprinted: Imprinted genes (Robert). **h1imr90enh: Enhancers in H1 and IMR90 cell lines (Robert). **salkaml: Additional DMRs based on Salk's BisSeq data and AML data (Robert). *Parameter file for probe design. *[[Media:probe2padlockCpgLibMay10.txt| Probe assembly script.]] *Probes designed and ordered for each subset: Designed Ordered Core.50k 170567 170567 H1IMr90Enh 8023 8023 Imprinted 3304 3304 SalkAml 52080 38106 Total: 233974 220000 *All 220k probes were split into four 55k libraries: **[[Media: DMR220k_probeSeq_a.txt.gz | DMR220k_a]]: OLID 0284601 **[[Media: DMR220k_probeSeq_b.txt.gz | DMR220k_b]]: OLID 0284591 **[[Media: DMR220k_probeSeq_c.txt.gz | DMR220k_c]]: OLID 0284581 **[[Media: DMR220k_probeSeq_d.txt.gz | DMR220k_d]]: OLID 0284571 *The probes were re-grouped based on the relative capturing efficiencies: **[http://genome-tech.ucsd.edu/LabNotes/upload/large_files/DMR220k_norm_probes.xlsx Probe efficiency and grouping info file.] **DMR220k.norm.s1_6500 0294691 **DMR220k.norm.s2_6500 0294701 **DMR220k.norm.s3_55k 0294711 **DMR220k.norm.s4_55k 0294721 **DMR220k.norm.s5_55k 0294731 **DMR220k.norm.s6_27k 0294741 **DMR220k.norm.s7_27k 0294751
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