Athurva Gore/LabNotes/2009-9-9: Difference between revisions

From ZhangLabWiki
Jump to navigation Jump to search
>Ajgore
No edit summary
>Ajgore
Line 4: Line 4:


=IPS and Cancer=
=IPS and Cancer=
* Need to check LOH mutations; is the new variant the damaging one?  Or the old one?
** If nondamaging version is lost, this is not actually harmful to the cell...
** Modified SIFT input to have fibroblast first, IPS second
** Can now easily check if damage is gained or lost.

Revision as of 21:03, 9 September 2009

Navigation

Exome Resequencing

IPS and Cancer

  • Need to check LOH mutations; is the new variant the damaging one? Or the old one?
    • If nondamaging version is lost, this is not actually harmful to the cell...
    • Modified SIFT input to have fibroblast first, IPS second
    • Can now easily check if damage is gained or lost.