Ns126:Calendar/NOTES/2015-6-26: Difference between revisions

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[[File:Density.CorrelationDifferenceBetweenCancerNormal.jpg|left|thumb|525px|Figure 1. Density plot for the correlation of high density CpG regions in 450K array between cancer and normals]]
[[File:Density.CorrelationDifferenceBetweenCancerNormal.jpg|left|thumb|515px|Figure 1. Density plot for the correlation of high density CpG regions in 450K array between cancer and normals]]
[[File:CorrelationDifferenceBetweenCancerNormal.jpg|right|thumb|525px|Figure 1. Comparison of the correlation for the high density CpG regions  
[[File:CorrelationDifferenceBetweenCancerNormal.jpg|right|thumb|515px|Figure 1. Comparison of the correlation for the high density CpG regions  
in 450K array between cancer and normals]]
in 450K array between cancer and normals]]



Revision as of 22:12, 26 June 2015


File:Density.CorrelationDifferenceBetweenCancerNormal.jpg
Figure 1. Density plot for the correlation of high density CpG regions in 450K array between cancer and normals
File:CorrelationDifferenceBetweenCancerNormal.jpg
Figure 1. Comparison of the correlation for the high density CpG regions in 450K array between cancer and normals


high correction region based on methylation 450K dataset

  • GSE53045 ( 50 smokers and 61 non-smokers, PBMC)
  • GSE32148 ()
  • GSE35069 Differential DNA Methylation in Purified Human Blood Cells
  • GSE36054 Methylation Profiling of Blood DNA from Healthy Children
  • GSE36064 Methylation Profiling of Blood DNA from Healthy Children (Harvard Age Study)
  • GSE41169 Blood DNA methylation profiles in a Dutch population
  • GSE44132 Antenatal Blood DNA Methylation Profiles
  • GSE42861


It is very interesting result: 1) cancer have two peak 2) cancer have more higher correction regions