Our Research

Located within UCSD Bioengineering, we develop technologies related to single-cell analyses of genome, epigenome and transcriptome,  as well as single-cell imaging and lineage tracing. These novel technologies are applied to stem cell fate conversion, human brain mapping and human disease studies.

Genomics and Informatics

We are developing various methods for synthesis, manipulation and sequencing of DNA molecules

Epigenomics and Transcriptomics

Our integrative epigenomic and transcriptomic analyses reveal dynamics of gene expression

Imaging and Lineage Tracing

We are developing technologies to track cellular fate decisions and transcriptomome dynamics in situ