CIRM BBAIII execution plan.: Difference between revisions
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==Year 1== | ==Year 1== | ||
* | *iPSC reprogramming. | ||
**Somatic cell types: Fibroblasts (PGP1F, BJ, IMR90), others?? | **Somatic cell types: Fibroblasts (PGP1F, BJ, IMR90), others?? | ||
*hESC differentiation. | **Reprogramming methods: 4F, 4F plus POLR1C shRNA, episomal?? | ||
*hESC/hiPSC differentiation. | |||
**H1 (need to obtain the cell line through MTA), Hues3, HUES8. | **H1 (need to obtain the cell line through MTA), Hues3, HUES8. | ||
*Exome sequencing and mutation validation. | *Exome sequencing and mutation validation. |
Latest revision as of 17:11, 27 June 2011
Year 1[edit]
- iPSC reprogramming.
- Somatic cell types: Fibroblasts (PGP1F, BJ, IMR90), others??
- Reprogramming methods: 4F, 4F plus POLR1C shRNA, episomal??
- hESC/hiPSC differentiation.
- H1 (need to obtain the cell line through MTA), Hues3, HUES8.
- Exome sequencing and mutation validation.
- Existing lines (what??) versus new lines.
- Gene knock-in/knock-down experiments.
- What genes??
- Build a database??